Weakness in the loins, and legs, cold lower part of the body (waist, legs and feet), tension in the lower abdomen, frequent urination or lack of urination, swollen tongue with pale coating, weak, slow pulse or deep and faint pulse in the che position (third position), phlegm retention syndrome, and flabby legs. Often chronic nephritis, advance diabetes, parasympathetic nervous system disorder, senile dementia, and other chronic disorders or urinary dysfunction can accompany above mentioned syndrome.

The other extreme condition is shenyinxu.

Patients with shenyangxu condition are more susceptible to anaphylactic shock.

cAMP is the abbreviation for cyclic adenosine mono phosphate, a cyclic nucleotide of adenosine that acts at the cellular level to regulate various metabolic processes and mediate the effects of many hormones; so it is also known as second messenger where hormones are the first messengers.